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Brazilian spotted fever prevention through a nonlethal capybara population control strategy
Rosenfield, Derek Andrew; Polo, Gina; Pizzutto, Cristiane Schilbach.
Affiliation
  • Rosenfield, Derek Andrew; Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Programa de Pós-Graduação em Reprodução Animal. São Paulo. BR
  • Polo, Gina; Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Medicina Veterinária Preventiva e Saúde Animal. São Paulo. BR
  • Pizzutto, Cristiane Schilbach; Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia. Programa de Pós-Graduação em Reprodução Animal. São Paulo. BR
Rev. Soc. Bras. Med. Trop ; 52: e20190156, 2019. graf
Article in En | LILACS | ID: biblio-1041580
Responsible library: BR1.1
ABSTRACT
Abstract

INTRODUCTION:

Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.

METHODS:

We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.

RESULTS:

The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.

CONCLUSIONS:

We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Rodentia / Rocky Mountain Spotted Fever / Gonadotropin-Releasing Hormone / Contraception, Immunologic / Vaccines, Contraceptive Limits: Animals / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Rodentia / Rocky Mountain Spotted Fever / Gonadotropin-Releasing Hormone / Contraception, Immunologic / Vaccines, Contraceptive Limits: Animals / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Rev. Soc. Bras. Med. Trop Journal subject: MEDICINA TROPICAL Year: 2019 Document type: Article Affiliation country: